Low-Dose Chemoreduction for Infants Diagnosed with Retinoblastoma before 6 Months of Age
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چکیده
منابع مشابه
Low-Dose Chemoreduction for Infants Diagnosed with Retinoblastoma before 6 Months of Age.
AIM The purpose of this study was to evaluate the outcomes of infants diagnosed with retinoblastoma before 6 months of age, including the need for chemoreduction (CRD). In this age group, dosage of CRD was reduced due to its potential for toxicity. METHODS This is a retrospective review from 2000 to 2009 that includes 126 eyes of 72 infants (18 unilateral, 54 bilateral). Systemic CRD was admi...
متن کاملChemoreduction for unilateral retinoblastoma.
OBJECTIVE To evaluate conservative management of unilateral retinoblastoma using chemoreduction and focal treatment. DESIGN Prospective nonrandomized single-center clinical trial. SETTING Ocular Oncology Service at Wills Eye Hospital of Thomas Jefferson University, Philadelphia, Pa, in conjunction with the Division of Oncology at The Children's Hospital of Philadelphia. PARTICIPANTS Thirt...
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Introduction: Anemia is common in both age groups of 9-24 months and adolescence. Considering the fact that anemia in children is associated with various complications such as stunted growth, activity intolerance, behavioral changes, inattention, irritability and changes in the immune response, the aim of this study was to compare the frequency of anemia in infants with normal birth weight and ...
متن کاملChemoreduction for retinoblastoma may prevent intracranial neuroblastic malignancy (trilateral retinoblastoma).
OBJECTIVE To evaluate whether neoadjuvant intravenous chemotherapy (chemoreduction) for retinoblastoma reduces the risk for associated intracranial neuroblastic tumor (trilateral retinoblastoma). DESIGN Retrospective consecutive case series. PARTICIPANTS Two hundred fourteen consecutive children with newly diagnosed retinoblastoma treated at a major ocular oncology center from January 1, 19...
متن کاملClinicopathologic features of retinoblastoma after primary chemoreduction.
BACKGROUND Primary chemotherapy is a new treatment approach in retinoblastoma, aiming to avoid radiogenic adverse effects, such as second tumor-associated mortality, as observed following external beam irradiation. OBJECTIVE To describe the clinical and histopathologic regression pattern after primary chemotherapy in retinoblastoma. METHODS Five patients with sporadic bilateral retinoblasto...
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ژورنال
عنوان ژورنال: Ocular Oncology and Pathology
سال: 2015
ISSN: 2296-4681,2296-4657
DOI: 10.1159/000370215